diff --git a/dvc/ignore.py b/dvc/ignore.py
index 2ec841349..d11c43053 100644
--- a/dvc/ignore.py
+++ b/dvc/ignore.py
@@ -39,6 +39,7 @@ class DvcIgnorePatterns(DvcIgnore):
                 for ignore, group in groupby(
                     regex_pattern_list, lambda x: x[1]
                 )
+                if ignore is not None
             ]
 
     def __call__(self, root, dirs, files):
diff --git a/tests/func/test_ignore.py b/tests/func/test_ignore.py
index d3a64435f..03b1e9567 100644
--- a/tests/func/test_ignore.py
+++ b/tests/func/test_ignore.py
@@ -166,3 +166,10 @@ def test_ignore_subrepo(tmp_dir, scm, dvc):
 
     for _ in subrepo.brancher(all_commits=True):
         assert subrepo.tree.exists(subrepo_dir / "foo")
+
+
+def test_ignore_blank_line(tmp_dir, dvc):
+    tmp_dir.gen({"dir": {"ignored": "text", "other": "text2"}})
+    tmp_dir.gen(DvcIgnore.DVCIGNORE_FILE, "foo\n\ndir/ignored")
+
+    assert _files_set("dir", dvc.tree) == {"dir/other"}